Combine 2 pounds of ground beef, 1 cup of panko breadcrumbs, 1/2 cup of milk, 2 eggs, 5 finely minced cloves of garlic, 1/3 cup of finely chopped parsley, 1/3 cup of grated yellow onion, 1 cup of finely grated parmesan, 1 teaspoon of salt, 1 teaspoon of dried Italian herbs, 1/4 teaspoon of black pepper and 1/4 teaspoon of red pepper flakes in a large bowl